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Polyphenols as Potential Dietary Cancer Prevention Strategy for Ethiopia: An Overview

Received: 22 November 2018     Accepted: 22 December 2018     Published: 22 January 2019
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Abstract

Polyphenols, the plant secondary metabolites produced by the shikimic pathway, are categorized into flavonoids, stilbenes, lignans and phenolic acids. Fruits, vegetables, grains, spices and herbs are now known as the good source of dietary polyphenols. Polyphenols exhibit their anticancer effects by suppressing the carcinogenesis process. They modulate multiple signaling pathways, induce apoptosis and prevent DNA mutations due to their anti-oxidant property. Because of high cost and limited success of cancer therapy it has become increasingly recognized that cancer prevention is cost effective. Promotion of healthy diet, i.e., eating variety of foods which are identified as good sources of polyphenols, in regular manner and in high amount is a potential cancer prevention strategy. In this review, the up-to-date findings on cancer fighting mechanisms of dietary polyphenols are summarized. In addition, the potential of Ethiopia in using dietary polyphenols as cancer prevention strategy is elaborated.

Published in Journal of Family Medicine and Health Care (Volume 4, Issue 4)
DOI 10.11648/j.jfmhc.20180404.13
Page(s) 33-38
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2019. Published by Science Publishing Group

Keywords

Polyphenol, Cancer Prevention Strategy, Carcinogenesis, Apoptosis, Antioxidant, Fruits, Vegetables, Ethiopia

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  • APA Style

    Gemechis Tesso. (2019). Polyphenols as Potential Dietary Cancer Prevention Strategy for Ethiopia: An Overview. Journal of Family Medicine and Health Care, 4(4), 33-38. https://doi.org/10.11648/j.jfmhc.20180404.13

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    ACS Style

    Gemechis Tesso. Polyphenols as Potential Dietary Cancer Prevention Strategy for Ethiopia: An Overview. J. Fam. Med. Health Care 2019, 4(4), 33-38. doi: 10.11648/j.jfmhc.20180404.13

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    AMA Style

    Gemechis Tesso. Polyphenols as Potential Dietary Cancer Prevention Strategy for Ethiopia: An Overview. J Fam Med Health Care. 2019;4(4):33-38. doi: 10.11648/j.jfmhc.20180404.13

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  • @article{10.11648/j.jfmhc.20180404.13,
      author = {Gemechis Tesso},
      title = {Polyphenols as Potential Dietary Cancer Prevention Strategy for Ethiopia: An Overview},
      journal = {Journal of Family Medicine and Health Care},
      volume = {4},
      number = {4},
      pages = {33-38},
      doi = {10.11648/j.jfmhc.20180404.13},
      url = {https://doi.org/10.11648/j.jfmhc.20180404.13},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.jfmhc.20180404.13},
      abstract = {Polyphenols, the plant secondary metabolites produced by the shikimic pathway, are categorized into flavonoids, stilbenes, lignans and phenolic acids. Fruits, vegetables, grains, spices and herbs are now known as the good source of dietary polyphenols. Polyphenols exhibit their anticancer effects by suppressing the carcinogenesis process. They modulate multiple signaling pathways, induce apoptosis and prevent DNA mutations due to their anti-oxidant property. Because of high cost and limited success of cancer therapy it has become increasingly recognized that cancer prevention is cost effective. Promotion of healthy diet, i.e., eating variety of foods which are identified as good sources of polyphenols, in regular manner and in high amount is a potential cancer prevention strategy. In this review, the up-to-date findings on cancer fighting mechanisms of dietary polyphenols are summarized. In addition, the potential of Ethiopia in using dietary polyphenols as cancer prevention strategy is elaborated.},
     year = {2019}
    }
    

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    T1  - Polyphenols as Potential Dietary Cancer Prevention Strategy for Ethiopia: An Overview
    AU  - Gemechis Tesso
    Y1  - 2019/01/22
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    T2  - Journal of Family Medicine and Health Care
    JF  - Journal of Family Medicine and Health Care
    JO  - Journal of Family Medicine and Health Care
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    PB  - Science Publishing Group
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    AB  - Polyphenols, the plant secondary metabolites produced by the shikimic pathway, are categorized into flavonoids, stilbenes, lignans and phenolic acids. Fruits, vegetables, grains, spices and herbs are now known as the good source of dietary polyphenols. Polyphenols exhibit their anticancer effects by suppressing the carcinogenesis process. They modulate multiple signaling pathways, induce apoptosis and prevent DNA mutations due to their anti-oxidant property. Because of high cost and limited success of cancer therapy it has become increasingly recognized that cancer prevention is cost effective. Promotion of healthy diet, i.e., eating variety of foods which are identified as good sources of polyphenols, in regular manner and in high amount is a potential cancer prevention strategy. In this review, the up-to-date findings on cancer fighting mechanisms of dietary polyphenols are summarized. In addition, the potential of Ethiopia in using dietary polyphenols as cancer prevention strategy is elaborated.
    VL  - 4
    IS  - 4
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Author Information
  • College of Medicine and Health Sciences, Ambo University, Ambo, Ethiopia

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